GTI's emphasis in End Use Solutions is on new technologies that improve efficiency, expand the natural gas product portfolio, increase the competitiveness of U.S. industry, and minimize environmental impact. GTI's program encompasses early stage research and innovation, technology development and deployment, commercialization support services, and technical market analysis.

GTI also manages projects for Utilization Technology Development (UTD), a not-for-profit company to facilitate voluntarily funded, collaborative research related to end use applications.